What Is Dopamine Deficiency?

Dopamine is an important brain chemical that helps control thinking, mood, and movement. Dopamine deficiency is found in several diseases including depression and Parkinson’s disease.

dopamine deficiency

Motivation, concentration, pleasure, euphoria, focus, and other positive feelings stem from our dopamine levels.

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You may have read or heard about dopamine deficiency and supplements or diets to increase your dopamine level. Dopamine is an important brain chemical, but other than a rare, inherited genetic disorder, there is no medical diagnosis called dopamine deficiency. [1-3]

You can develop low levels of dopamine or an inability of your brain to react to dopamine, but this occurs as part of a disease process along with other changes. Two common disorders that include decreased dopamine are depression and Parkinson’s disease. Abuse of drugs like opiates and cocaine can also lead to dopamine deficiency. [1,2]

Genetic Dopamine Deficiency

The genetic disease that causes dopamine deficiency is extremely rare. In fact, there have only been about twenty cases diagnosed. It is called dopamine transporter deficiency syndrome, and also called infantile Parkinsonism. Like adult Parkinson’s disease, this disease causes abnormal muscle movements. It usually starts in infancy or childhood and gets worse over time. The most common symptoms are sustained cramps and muscle spasms. Over time, this condition becomes similar to adult Parkinson’s disease. [3]

What Does Dopamine Do?

Dopamine is an important brain chemical that carries messages in your brain, called a neurotransmitter. Dopamine is important for many brain and body functions. Signs and symptoms of a dopamine deficiency disease may include changes in:

  • Movement control
  • Coordination
  • Mood
  • Motivation
  • Thinking
  • Attention
  • Memory
  • Sleep

In addition to contributing to the cause of Parkinson’s disease and depression, dopamine deficiency has also been linked to drug abuse, schizophrenia, autism, restless legs syndrome, and attention deficit disorder (ADD). Dopamine deficiency includes loss of dopamine production as well as loss of nerves to respond to dopamine release. Dopamine production decreases gradually with age, which may be one reason why Parkinson’s disease occurs in older adults. [1,2,5]

Dopamine Replacement

Unlike a vitamin D or calcium deficiency, dopamine can’t be easily replaced with a food or supplement. Dopamine is naturally produced in your brain. When dopamine is released in your brain it acts on specific dopamine receptors. [1,4,5]

Man-made, synthetic dopamine is available as a drug, but it is not used to replace dopamine because it is unable to pass from your blood into your brain. When taken as a drug is causes an increase in blood pressure and heart rate. It is used in several conditions where heart rate and blood pressure are too low. [4,5]

How Are Dopamine Disorders Diagnosed and Treated?

Although there is a blood test that can measure dopamine, doctors rarely order this test because dopamine levels in blood don’t tell much about how dopamine is functioning in the brain. Dopamine disorders are usually diagnosed by their symptoms. [1,2]

There are many possible symptoms depending on the disorder. You may have changes in thinking, mood, or movement. Each dopamine-related disorder has its own treatment. Antidepressants and mood stabilizers are used for mental health disorders. Since dopamine as a medication does not get into the brain, Parkinson’s disease is treated with a medication (levodopa) that can cross into the brain and be converted into dopamine. [4,5]

Although there are many supplements or diets that claim to increase dopamine levels, there is no strong evidence that any of these are effective. [1] Symptoms of dopamine deficiency require a careful diagnosis, since they could indicate a number of serious conditions. If you have signs or symptoms that could be due to dopamine deficiency, talk to your doctor. The good news is that effective treatments are available for many of these disorders. [1,2]



  1. Good Therapy, What Is Dopamine Deficiency? Low Dopamine Symptoms to Watch For
  2. Medical News Today, Dopamine deficiency: What you need to know
  3. MedlinePlus, Dopamine transporter deficiency syndrome
  4. Medical Life Sciences, What Is Dopamine?
  5. Oxidative Medicine and Cellular Longevity, The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress

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Chris Iliades, MD

Chris Iliades has an MD degree and 15 years of experience as a freelance writer. Based in Boothbay Harbor, Maine, his byline has appeared regularly on many health and medicine … Read More

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  • The most destructive habit that will lead to a dopamine deficiency is masturbation, especially if it involves pornography. If you have an addiction to either, it will act as a drug and your brain will alter dramatically and deplete you of dopamine. I suffer from dysthymia along with bouts of major double depression. Eliminating sexually addictions has helped me immensely after battling years of depression.

  • These articles never mention which doctors or clinics will address or test for deficiencies. Even at UCLA, my psychiatrists (I’ve had a few different ones) showed no interest in addressing root causes,, preferring only to prescribe the common drugs. Where are the doctors who apply this research?

  • Very great post. I simply stumbled upon your blog and wanted to say that I’ve really loved browsing your blog posts. After all I’ll be subscribing for your rss feed and I am hoping you write once more soon!

  • This is helpful. I went to my doctor with depression, I believe low dopamine, he just wanted me to take a pill. I am going to try all of the above. Thanks again

  • 2-3 cups of coffee at work give me a buzz that makes me feel positive, sociable, and productive. Pre-workout drinks on an empty stomach also give me sustained energy and focus. I’ll have to try multi-vitamins to see if they work on my anxiety.

  • I was so depressive that I was unable to sleep, quarrelled and even thought of suicide. Then one Christian leader told me that the root cause of depression is not praising the GOD. I got up early in the morning around 6 am and read 1 Chapter from Psalms and 1 Chapter from Bible Gospels everyday in low voice. Then I do praise and worship of God Jesus for some 7 minutes . Believe me my depression vanished over a period of three months. This is the most suitainable natural remedy and I’m the proof. Praise the Lord Jesus.

  • I was so depressive that I was unable to sleep, quarrelled and ate like an elephant. Then one Christian leader told me that the root cause of depression is not praising the GOD. I got up early in the morning around 6 am and read 1 Chapter from Psalms and 1 Chapter from Bible Gospels everyday in low voice. Then I do praise and worship of God Jesus for some 7 minutes . Believe me my depression vanished over a period of three months. This is the most suitainable natural remedy and I’m the proof. I’ve prescribed the same to a man with suicide tendencies and it worked for him too. Praise the Lord Jesus!

  • Thank you. will follow the advice on exercise, 7 hr sleep and following a routine. Fully agree with Mike( June 23, 2016) The most destructive habit that will lead to a dopamine deficiency is masturbation, especially if it involves pornography.

  • With all this technology it seems there would be a way to test for low dopamine, serotonin, etc. instead of trial and error with endless anti depresants over months and years. No wonder the suicide rate is so high.

  • I was prescribed hydrocodone-acetaminophen for pain. I felt wonderful, happy, relaxed, peaceful and energetic. However, I grew resistant, needing higher and higher doses. I am off medication now and trying to find healthy alternatives. If anyone else has had success, I would appreciate input.

  • Jim, I couldn’t agree with you more. This is the frustrating part about having this illness. The doctor’s only seem to want to push pills instead of doing actual tests to find the root of the problem. I recently started taking some anti-depressants, as well as anxiety meds, which work for a month or two, but then after taking them everyday, the high tolerance to the pills makes them ineffective.. Then what? Try something else that may or may not work. It’s an endless wild goose chase for happiness. I’ve been smoking marijuana for many years, and honestly, it’s the only thing that makes this “monster” that I feel like I am, finally subside for awhile, and I can live a normal life. From experience, I can tell you that this does work, maybe not for everyone.. but if you’ve reached your breaking point, and you feel there is no hope for you… let your pre-conceived notions go, do some research on it, and find out if it could help you too. I’d be 6 feet deep right now if I hadn’t discovered marijuana, and that’s just the harsh truth.

  • I find taking phenylalanine, tyrosine and magnesium very helpful. Also, exercise, decrease stress and DEFINITELY decrease sugar intake. I’m pretty sure this bout of depression was brought on by my high sugar intake over the holidays. I also do have an autoimmune thyroid condition and gene mutation which affects my liver’s ability to break down stress hormones so, this is an ongoing struggle for me between intense anxiety and complete apathy. Highs and lows. It’s much better when I am on a strict diet but I get lulled into feeling like I can handle it and, before you know it, I’m like Will Ferrel’s Elf pouring maple syrup on spaghetti. (Not literally…I don’t eat spaghetti)

  • Great article thank you. I have really low dopamine levels. I was taking dr cabots liver tone and was wondering why I was lot more motivated and feeling better. It’s the turmeric in it.
    I’m also very low on magnesium. Every damn night I have cramps. I get sick of popping pills. But. I need to get my magnesium insurplus I guess and then I can down the dosage. I’ll target my magnesium levels and get them up. See how I go. Thanks to all those that commented. Helped a lot ?

  • Beth: I have Bipolar & major depressive disorder. As I have not had the mania in several (7) years & been very depressed my psychiatrist switch me back to Prozac. A month ago I began taking magnesium separate from my bipolar meds as well as taking my other vitamins hours before or after taking my prescription meds (depakote, xanax). How do the supplements work w/ prescribed meds? Doctors just blow me off when I ask about vitamins.

  • I have found that vitamin B injections twice a month help. Also eating protein at each meal, small
    meals thru the day. Magnesium helps relax so can sleep. 30 minutes of whatever exercise one is able to do daily. Doing whatever makes you happy every day also. Also massage, reflexology are good too. Best of luck

  • From a young age I realized that I was always a lot “lower” than everyone else. I was always tired, got sick easily, and generally unhappy. In my teens I discovered alcohol and drugs and felt better than I ever did…. for about a decade. Then that came crashing down on me as alcoholism and addiction will. So I quit it all, went to meetings, “found God”, etc. but my health went on me. It was like I was pickled all those years and when I stopped my body fell apart. Like you see in the movies where a car takes beating after beating as its driving and then when it finally stops the whole thing falls apart, doors, wheels, and all. That was me in a nutshell. Here I am 17 years later at 45 years old wanting to just die and get it done with. I won’t commit suicide but I have so many problems now I cannot work and am a useless piece of meat.
    I just got a DNA test done through my Dr.s office. They went thru the company Proove Biosciences, Inc. · Proove Medical Laboratories, Inc in California and I am not shocked at much. It shows I have low serotonin, dopamine, etc. which makes perfect sense as the only time I felt how people normally did was when I was starting to catch a buzz.
    So what am I supposed to do? I am in too much pain to work never mind exercise and I cannot do anything at all anymore before I am pale, shaking, out of breath, and feeling like I am going to pass out. I have all types of issues wrong with me so things won’t get better soon but at the same time I don’t want to die because there is too much I want to learn and see but at the same time I cannot deal with going on like this either.
    I guess there isn’t any answer and I’m not really expecting anyone to have one… but sometimes we’re just behind the rest of the pack “right out of the gate” (as in a dog race)… it sucks that I can only feel normal when high and I cannot even go that route anymore either as I am married to one unfortunate woman and seeing as she already married a lemon I don’t want to make her life worst by me returning to that life. I don’t want to return to it either though as too many bad things happened at the end and all of the good times were long gone but one can’t help but wonder if it is my only way of having a life.. as what I have now is no life at all.

  • Hi Joe S.
    I just happened upon your comment today. You are a valuable life and worth so much more than just a piece of meat. You will recover but you will have to rebuild yourself bit by bit over time, don’t expect to fix it all at once. Begin with what the tests revealed – the serotonin and dopamine levels. Get your Dr to recommend good anti-depressants that will begin to redress the imbalance in these. Once things are improving there, maybe you can start to work on one aspect of your health – e.g. diet, exercise etc, but again, don’t set yourself impossible goals. And keep loving your wife. She saw good in you to make a life covenant with you, you do have it within you to lovingingly serve her, as she does you.
    You’ve “done God” but He hasn’t done with you. You are worth something; you are special and unique. Be well!

  • Joe S:
    I think I know how you feel, and I’m so, so sorry. I sincerely hope you are doing better and have found some ways to improve your life. Reality can be harsh and it’s certainly far from fair. The only advice I can think of that might help is this: you have to keep trying. Not to have a life like someone else’s, but just to live as well as you can under your own circumstances.

    I hope this helps a little.

  • I have found Keto (no sugar, no grains, etc. ) helpful. Also for the person previously, pickle juice is great on muscle cramps. Am 60 and am ADHD. Started adderall for the first time (low dose). While it is working, I would like to go without and need to increase dopamine to do so. Good article. Thank you.

  • My doctor prescribed Tramadol off label as an antidepressant since those don’t work well for me. I am not addictive. I was in a dreadful situation that kept me depressed, crying, and without energy. One Tramadol tablet gave me the backbone to get up and do what needed to be done. I have changed my situation and get by fine on most days without any Tramadol. I do take one tablet or half one on hard days. I also take L-Tyrosine and vitamins. Guess I need to add magnesium. I feel sure I have low dopamine and seratonin. Tramadol increases seratonin. Enjoyed reading this blog.

  • I have to do a gratitude practice every day to keep me from going under plus a really good diet, and adding supplements this year has got me even stronger. I got myself a hair mineral anaylsis done at a reputable company in the US, and practitioners trained by the company work out the minerals the person needs from there hair analysis results. All vits and mins were pretty much depleted for me, and mercury and aluminium were too high which can also cause crazy brain upsets.

    Also, if I can get up with or before the sunrise I do so much better the rest of the day. They say there’s an uplifting energy in the air before sunrise and I believe them. If I had the energy to, I’d get up at 4:00am to get as much of it as possible but my energy would be obliterated by the afternoon. I remember reading a study on depression where participants were asked to get up at 2am every day (and to bed very early of course) and their depression vanished.

    The gratitude practice I do is from Andy Shaw’s A Bug Free Mind where you think of things in your life that bought you joy – can be the teeniest or obscure moments – can be in childhood or any other period in your life – and you gather as many of these as possible, and think upon them one at a time, with the intention of having feelings of joy/gratitude for 15 mins at a go.
    The energy of gratitude is a joy that apparently can gradually gradually dissolve and heal.

  • At 56, I have suffered from depression on and off, all of my life. At times, its gone and I feel as though it will never return. But it does. And when it does, it can deep, dark and take months to recover from. Recovery required concerted effort on my part to bring me back to balance.

    I am a coeliac and am hypoglaecemic. I was incredibly fortunate to be treated by an Orthomolecular Psychiatrist (OP) for about 6 years, until he stopped practicing and subsequently passed away. He did give me many of the answers. My simple understanding of OP is that it seeks to have all things in balance in the body – vitamins and minerals. My specialist tested for deficiencies in both and auto immune diseases, along with lots of things I can’t recall. He changed my diet dramatically and prescribed vitamins and minerals. When I followed his advice exactly, I was a different person within 6 weeks. I jumped out of bed and dealt with life and stress happily and with energy. I lost weight very quickly without dieting (my weight had been out of control since pregnancy). I was a single parent in unstable housing, living in poverty and studying a high level degree at the time, so lots of stress.

    The 8 steps here all worked. For me, with Coeliac’s and hypoglaecemia, I needed to make other dietary changes. They worked. One of the most stunning changes was taking sugar 100% out of my diet. The low level of depression I was living with disappeared. These days, I probably only take sugar in alcohol, which I haven’t managed to give up completely. Wish I didn’t enjoy it but I do. And yes, it does knock me around. For me, more than one bottle of dry wine a week is a no-no. That’s just me.

    When I’m on my diet and supplements path, I do really well. I look younger than my years and my weight is in check. At times though, I wander off my path and I really suffer for it. Sometimes, I want to pretend I’m normal and can eat whatever I want. That never extends to wheat or gluten but dairy knocks me around pretty badly, as do many other things. If I eat dairy, grains, carbohydrates of any description, beef, corn, fried food, anything which raises blood glucose levels (carbs, sugar, fruit, honey etc) and drink even my small quantities of wine, I drop into depression within a week. It can take quite a while to haul out again. And lets face it, when you’re down there, you’re down there alone. No-one is coming in to help or guide you out. Loneliest place on the planet. Such a waste of life.

    Long story short? For me, natural things like diet, supplements and exercise help dramatically but you need to stick to it. That’s the bit I’m not always good at. Mia culpa.

  • Dear Joe–

    Nutritional supplements may be beneficial for you. Our bodies need micronutrients to make the various neurotransmitters, enzymes, proteins, energy that we need–and these can get severely depleted in the course of living. Stress, lack of sleep, depression, age, coffee, sugar, addictions all take a toll.

    I urge you to take a look at this book, which has been very helpful to me. (And despite the name, the book is useful to nonaddicts as well.)
    You can scroll through the table of contents on the Amazon site. It’s a lot to take in at once–I have reread it several times and keep it on hand as a reference.

    You might also consider consulting with a naturopathic physician to get recommended supplements. (Medical doctors don’t usually subscribe to nutritional therapies for various reasons.) Also, a medical doctor or therapist if you feel emotionally at risk.

    I have been through a severely stressful decade that left me barely functional. Then I started reading about nutritional remedies for my ailments, and began feeling better immediately when I started taking supplements. Over the past year my health has improved enormously, and though I still have a ways to go, it has been therapeutic to be active in my own healing. I keep a running list of which supplements I’m taking and why, and update it every month or so as things improve or not.

    It is very positive that you are reaching out for help. Please don’t despair. I think you will succeed. Good luck to you.

  • I lost my imagination power,poor cognition,memory & brain power after treatment for very high dopamine level & of old.THE WRITINGS ON THIS WEB PAGE IS SO HELPFUL FOR ME I ASSUME NOW I HAVE. A DOPAMINE DEFICIENCY IN ME I GAIN VERY CV WRIGHT TOO.I AM SO DEPRESSED NOW

  • Sorry for typing mistake,i treated for ocd &high dopamine level after treatment my dopamine level shot down highly now I am very depressed l have suicidal tendencies some times i lost my imagination power what to do

  • I have also heard that low dopamine levels can lead to obesity as a person who has this problem is never satisfied; they are always hungry. My youngest son may have had this problem of low dopamine levels because he was very depressed and weighed 500 lbs., and died when he was 38 years old of a heart attack.

  • Took a screenshot of the popup “no thanks i dont want to be happy or healthy” for declining your ad. Will be sending it to my lawyer if it not changed in a reasonable time. Ill give you two weeks.

  • Hello David (February 9). Jehovah God hears our cries, when we call unto Him in the name of Jesus Christ. If we confess our sins to Him, He is faithful and just to forgive us and create in us a new being. A new being full of hope and peace for a better life even here on Earth. I would like to encourage you to read the book of Job in the Old Testament of the Holy Bible. I have often found it encouraging when I am at a low point in life. The man Job lost his children and all of his belongings. He was afflicted by a terrible disease but he got through that difficult time because he sought his strength from Jehovah. Trust and hope in Jehovah, David. He will give you the strength to live each day. I pray that you have peace and joy in your heart, and you are healed of all your sicknesses in Jesus’ name Amen.

  • Hello Joe S. (February 6). Jehovah God hears our cries, when we call unto Him in the name of Jesus Christ. If we confess our sins to Him, He is faithful and just to forgive us and create in us a new being. A new being full of hope and peace for a better life even here on Earth. I would like to encourage you to read the book of Job in the Old Testament of the Holy Bible. I have often found it encouraging when I am at a low point in life. The man Job lost his children and all of his belongings. He was afflicted by a terrible disease but he got through that difficult time because he sought his strength from Jehovah. Trust and hope in Jehovah, Joe S. He will give you the strength to live each day. I pray that you have peace and joy in your heart, and you are healed of all your sicknesses in Jesus’ name Amen.

  • Hello Joe S (February 9). Jehovah God hears our cries, when we call unto Him in the name of Jesus Christ. If we confess our sins to Him, He is faithful and just to forgive us and create in us a new being. A new being full of hope and peace for a better life even here on Earth. I would like to encourage you to read the book of Job in the Old Testament of the Holy Bible. I have often found it encouraging when I am at a low point in life. The man Job lost his children and all of his belongings. He was afflicted by a terrible disease but he got through that difficult time because he sought his strength from Jehovah. Trust and hope in Jehovah, Joe S. He will give you the strength to live each day. I pray that you have peace and joy in your heart, and you are healed of all your sicknesses in Jesus’ name Amen.

  • Due to chronic depression diagnosed when I was 32, I started trying almost all. But I don’t like medicine. Especially not pills that numb you. I’m still new to supplements (and I hope they work). However, recently I discovered a yogic breathing technique called “bhramari kumbhaka” (humming bee breathing technique) that is amazingly helpful to overcome moods swings, anxiety, and irritability (or anger). It doesn’t help with: lack of interest in life and decreased motivation but it does keep you feeling deeply calm and peaceful (even in stressful situations). It would be amazing if your University team would consider doing a study on why these yogic breathing techniques impact our brain, calming us down. But I’m posting this comment primarily for all the people out there who are in pain due to the devastation rooted in depression and the helplessness that arises when you’re incapable to overcome it. OM AH HUM

  • Doctors Gabor Mate,MD, and Gordon Neufeld, Ph.D. in Developmental Psychology, both with about 40 years experience say that we are designed to get endorphines to our brains through the attachment connections, and when we do not, we have deficiencies. When we seek to fill this need through other means can bring a temporary fix, but there are always side-effects. These are not fulfilling and become addictive. I’m not saying to never take medicine, just likely when you understand what is happening, you might not need it over time after taking corrective measures. You can read their book: Hold On to Your Kids or hear one of their lectures on YouTube. They are both international keynote speakers. I think their book is translated into about 14 languages. Dr. Mate’s book, When the Body Says No, is translated into 29 languages. These are research based, scientific books that are self-evident and resonate with people.

  • I am really impressed with the common decency shown by the comments in support of one another after reading this article. I’ve taken notes on life style changes and supplements mentioned. I have suffered from some form of depression my whole life and i have internalized those feelings into a belief system that I am inferior, not smart enough, overweight, incapable of finishing anything, unlovable and worthless. I have struggled to fight these feelings and have made some progress and have achieved some accomplishments but its a daily struggle and as I get older it gets harder. I am seeing a therapist but I believe her abilities are limited. I now believe I have a low dopamine and serotonin condition and hope I can find the right physician to help. I’ve seen some religious messages in the comments and I do support faith as a rudder to help us but I can see how too much can turn people away. A more subtle message may be more powerful. God helps me in ways that I cannot ever begin to count this is how I know God loves me, I’ll leave it at that. Best to all of you, please continue to share what works.

  • Thanks for the valuable information , this will help so many people to make their life better .
    Good Work

  • My daughter’s doctor recommended that she take an anti-depressant. Because my daughter had previously had some unwanted side effects from other drugs, I was unhappy for her to go this route. I went online and saw that something called SAMe seems to be helping many people. Although some people do have side effects, it sounded more natural (it’s sold over the counter) than what the doctor was suggesting. I believe it’s not recommended for people with psychosis. My daughter hasn’t been using it long enough for us to decide if it’s helping or not, but it may be worth for other people with depression to check it out.

  • Ive started thrashing out in my sleep acting out my dreams… a bit of research has led me to the point that REM sleep is disturbed as in its a parasomnia. Im worried about hurting my partner as I sleep. Lst night I pulled a lamp off the table.. last week I kicked really hard a set of drawers injuring my foot. Disturbingly Ive seen it be a poss early symptom of parkinsons disease or dementia.. and that worries me. So researcdh has led me to this page.. so from now Im going to look at exercise.. caffeeine withdrawal.. alcohol withdrawal and eating good foods to increase dopamine……

  • The only problem which wasn’t mentioned is this. dopamine by itself is very unstable in blood stream therefor it decomposes before it riches to brain. The best method is using combination of L dopa and Carbidopa. Carbidopa is a type of protector of dopamine which stays with it until in brain releases dopamine.

  • I like you have put this out. Natural ways to possibly increase dopamine are great, compared to say L-dopa or other drugs. I just want to say a few things. Dopamine is a complex beast. We are still trying to figure out how its receptors work. It is also found not only in the brain, causing more complexity (for instance in the intestines, where more dopamine is not a good thing). In the brain, it has 4 major pathways, effecting reward, motor, cognition and weight\body mass. In these 4, different levels are optimal. So a certain level good for one can be bad for another. If you somehow know the problem is not enough dopamine, this article is great. However, it is usually way more complex than that. Say you have enough dopamine, but not enough DRD1 receptors. Than dopamine will have less effect. Guess I am saying, it is usually not a simple matter of having too much or not enough dopamine. It is great natural ways can increase dopaminergic function, though.

  • I was diagnossed with major deppressin and ADD on Amen Clinics.
    The diagnse was mada throght a scan where they saw my neurotransmissors desconected. The send me something called SAME. This is an aminoacid which helps produce dopamine. The also sent me Tyroxine. I buy all at their web page. I feel super good in very short time. Full recomended.

  • For the past 20 years I had been taking allergy shots and they had helped to keep my lungs clear, but after moving across country and being tested by two separate allergists who said I didn’t have allergies, but chronic obstructive pulmonary disease (COPD) my allergy shots stopped. One and a half years ago I started sweating profusely, worse than during menopause. Water literally dripped off my face. Gradually it started to disappear. The less the sweating became, the more I became breathless until I was gasping for air walking across a room. My lungs started to fill up with mucus which eventually turned into pneumonia. I lost touch with reality.I started on Health Herbal Clinic COPD Herbal formula treatment in May 2017, i read alot of positive reviews on their success rate treating COPD disease through their Herbal formula and i immediately started on the treatment. Just 7 weeks into the Herbal formula treatment I had great improvements with MY breething ,I am unbelievably back on my feet again, this is a breakthrough for all COPD Patients, visit Health Herbal Clinic official website www. healthherbalclinic. net

  • I’ve been involved with spiritual healing for a number of years. The most prolific healer in recorded history recommended loving your neighbor and loving God..If you go beyond religious belief paradigms, you may see that God is yourself. So, love yourself and love everyone else – actively. This is the real key to physical and emotional healing – but you have to do it at a very high level in order to see practical, real-world results. You can use every moment of your life to practice this. Read ‘Love Can Open Prison Doors’ by Starr Daily – I think you can still read it for free online. He talks about the technique of sending love out to everyone as much as possible. One thing though – To really be able to do this technique consistently, it REALLY helps to be in an up/energetic mood/mindset. To that regard, some of the natural supplements mentioned here can be helpful. Magnesium, niacin, tyrosine, SAM-e, etc. But if you can get your hands on some Nutiva Hemp Oil, you may find a remarkable difference. It’s available at the Vitamin Shoppe if you are in the USA..or you can just order it on Amazon. A tablespoon in the morning and at night can work wonders for depression. Just search the internet for people using Hemp Oil (not the more expensive CBD oil) for depression. Best wishes.
    p.s. – That healer I mentioned, you can hear a lot about him on youtube. His name was Bruno Groening. Many people believe he was the last incarnation of the big JC. I’ve had numerous mystical experiences with him over the years – I can tell you he’s the real deal.

  • Around age 60 I noticed that my handwriting was getting smaller and I was writing faster. I also noticed a small tremor in my right hand. The doctor went over my different symptoms and he suspected I’d either had a small stroke or the beginnings of Parkinson ‘s disease. After finding a neurologist and some testing I was diagnosed with the beginning stages of Parkinson’s disease. That was 4 years ago. I take Sinimet four times a day to control my symptoms, which include falling, imbalance, gait problems, swallowing difficulties, and slurring of speech,December 2017 our family doctor started me on Mbeki Herbal Clinic Parkinson’s Disease Herbal mixture, 5 weeks into treatment I improved dramatically. At the end of the full treatment course, the disease is totally under control. No case of dementia, hallucination, weakness, muscle pain or tremors.

    Visit Mbeki Herbal Clinic official website w ww.mbekiherbalclinic .com. I am strong again and able to go about daily activities.‌ This Herbal Formula is Incredible!!

  • I have had emphysema for about five years. I was on oxygen during the day but not at night. I could go about two hours without the oxygen, and then I need it. I had a converter in the house and oxygen tanks for when I go shopping, etc. I am 64 years old and in relatively good health. The doctor said it was caused by a combination of smoking, dust here in Vegas, and 30 years of smog in California. I believed I will always need the oxygen to breathe. I quit smoking 15 years ago. But the damage has been done. January 2017 my pulmonologist and I decided to go with natural treatment and was introduced to Green House Herbal Clinic natural organic Emphysema Herbal formula, i had a total decline of symptoms with this Emphysema Herbal formula treatment. Visit Green House Herbal Clinic official web-site ww w. greenhouseherbalclinic. com. The infections, shortness of breath, fatigue, dry cough and other symptoms has subsided.  I am very pleased with this treatment. I breath very well now and exercise regularly, sometimes i totally forget i ever had Emphysema, I am thankful to nature, the medics failed. Share with friends!!

  • To balance your mineral needs eat a banana at night – which helps you sleep – and get plenty of fresh pineapple during the day. (Like a whole one!)
    Check out the nutrients in both and you’ll see why. … or – just try it.

  • I had my thyroid burned out radioactively for hyperthyroidism, now I am hypo and take Armour Thyroid. I have restless leg syndrome very bad. I have stiff joints. I tend to feel somewhat depressed, have no energy, motivation, enthusiasm. I crave sugar, and am fighting a gambling addiction, thus pretty sure I have low dopamine and seratonin levels. I also would guess I’m storing magnesium in my cells and it is not being utilized in my body as it should be. Interestingly enough, every time I go through a scanner at the airport it shows metal in my most fatty areas of my body. I want help! I don’t know where to turn. Regular doctors are not getting to the core of my problems.

  • Julie K. I would look into the scanners showing metal in your body, talk to your doctor about that if you haven’t already. If you solve that issue it might help with other problems. It also sounds like you do have dopamine problem. Good luck.

  • Julie, I also have RLS and am on meds for low thyroid. Some meds for RLS are known for side effects of causing impulsive behavior like gambling. Perhaps a different type of Rx will help?

  • Nicotine–note I did NOT say tobacco. Multiple peer reviewed studies show efficacy in issues such as dopamine related depression without the health effects of smoking. When researching make sure you are reading about nicotine not tobacco or smoking. A nicotine patch or lozenges are effective means of increasing dopamine.


  • I believe articles on this site, as it is uhnews. So maybe you say the correct /truthful things. Does not appear as if you are being paid to write incorrect data. Anyways.

  • I’m 26 and feel like I’m going through a midlife crisis. The only things I can do is lay in bed and think about how terrible life is. Can’t sleep. Have no energy. Started taking adderall because I found through research that it really helped people with problems. I was diagnosed as a kid with adhd and was never put on any medication. Which I’m greatly appreciative of. I think. I am not addicted because I know I can put it down. But I why would I? I know I will be ok if I don’t have it. That’s not the issue. I went to adderal because of the same feelings that come back when I’m off it. I’ve always been a deep thinker. There’s something I’m not seeing clearly and I’m just masking my issues and I cannot figure out what it is. I went through a break up and that really hurt and that’s what started me looking for a solution. When I found adderall it restored my faith in myself that I could be happy and function. But after I had been on adderall for about 3 months I started coming down off the “high” I had from experiencing a new stage of life and I started thinking about LIFE again. Not about a girl anymore but life. So now I’m on adderall, I’m becoming less active, less motivated, but all the while my brain is still processing many many things at once and I focus on a hundred different thoughts and play out those thoughts in my head. And I love it. It’s good to plan. But I get to the end and realize that path is not what I want and I get this huge overall sensation of depression for about 1 second because I think I’ll never find a solution. And it consumes ALL of me for such a short amount a time. It’s like I’m on the verge of sever suicidal thoughts and every now and then I slip off the edge. And it happens everyday. Worse when I’m on adderall. So obviously it makes my anxiety worse. Usually up to 20 times a day. One of my issues is not knowing what I want to do for money to survive this world. I’m very talented at almost anything I want to become good at. I was that kid from a small town who was good at every sport growing up. I flipped cars when I was 15 and flipped houses when I was 22. Everyone knew my name. Somewhat of a celebrity in my little town. Anyway I made it out of that town with aspirations of MLB or NFL and my junior and senior year of college I had two consecutive season ending injuries. The last one did it in for me. NFL chances were within reach and mentally I wanted it but I knew physically I couldn’t. Most football players agree that every practice is like being in a car wreck. Been playing since I was 7 so you do the math. Completed 19 out of my 19 total years of preparation I had available to get to the nfl and in the last moment my dream was ripped out from under me. But in reality…it was just the beginning. Now, I got thrown into this scenario where I have to do things I don’t like in order to function in society. Like find a career that I have to do everyday all day in order to stay alive. And when I try to pick one of my talents to focus on…I play that “life” out in my head and realize I don’t want to do that for the rest of my life. Every. Single. Option. Fails. I just want to go back to how I saw the world as a kid. I want to be happy again. I want to be a dreamer. I just moved back into my moms at home and have 3 little brothers and sisters. They are so happy usually. And when they’re upset it’s over irrelevant things. What happened to that? What happens to us as we grow??? Why do we lose the adventurous, courageous, spontaneous, colorful life we grew up with?? It’s society. The whole world really. I am a very very deep thinker and I feel like I’ve found the truth to life and it’s depressing as all get out. I feel as though I lost my will to live. I look around at the world and what a terrible place it is. People slave all day just to get a few hours at night to relax and sometimes be around family. Some are worse than others. People deal with death in their family, families are apart most of the days with work and school, debt they can’t get out of, severe depression, poverty, it’s 2019 and people still give af about what color your skin is…it’s endless. People think they have the right to judge. God says he who judges another is judging me for I am the Holy Ghost and the Holy Ghost is you. The only people you see happy are the smiling faces Sunday morning and the rich and famous. And most of the time it’s all a front. I came across this post because I had enough and I just want to learn why I feel the way I feel. Why do all of us live this life? What is the point? I am not talking suicidal I’m just openly talking and asking opinions. I hit a real hard point in my life recently and when I got officially diagnosed with adhd and minor depression I asked to be on adderall. So after I started taking it consistently my mind improved, my mood improved, I wasn’t over endudgeing on food, I was able to shut out the part of me that was always thinking about life and what it is and what I’m doing with it. I felt normal for once. I was going through the motions. But after a while I realized I didn’t want to be normal. I didn’t want to live a busy life just so I can ignore the pain I know is there. I don’t want to be like the other zombies that slave all day. Lots of people say on here that you just have to push through. Why? How? For what? What are we pushing through for? Just to ignore the pain we know is there?? We walk this earth with programmed life and expect to be happy. It’s like we’re all born into a job. People used to roam the earth and claimed things that they made or killed. Now you can’t even collect rain water without the potential of getting arrested. People “push through” these thoughts and wash them away and become completely consumed by society and then before it’s too late.. earth consumes us(death). Are we just supposed to push through till it’s over? I wasn’t to enjoy and cherish not push through. If life is just a lesson can we not fail? How do you decide what to do with your life fully knowing you’re just going to work until you die? Knowing currency and debt rule all now. Who thought they were God and could change the world? Everyone these days are so selfish (usually forced to be) and it’s so depressing. I don’t think I would ever free myself from this world voluntarily but if you knew when you left you’d be going to a better place..it’d be hard not to say bring me death. My main issue is I have no will to live. Not that I want to kill myself..but I’ve just lost my drive. And I can’t find a way out of this deepening hole. I show all signs and symptoms with everyone on this post under 50 yrs and I’m going to try the things other people have said to improve my wellbeing. I’m glad I came across this. Maybe someone will see my story and feel comfort that they aren’t the only one. I know I would.. cause right now I feel like it’s me against the world and damn that shit is getting heavy.

  • Shane,
    First, I’d like to say… great message. Deep stuff.
    I think you’re going to be okay, especially with so much wisdom and such theological thinking you got, you’ll be just fine. I’d recommend not focusing on the world or how terrible it can be (of course, that is, in your perspective) but focusing on how YOU can make the world a better place. You could write a book on your struggles, hopes, dreams and influence hundreds, thousands of people! You could impact people in more ways that you can imagine. And while I write this, I will say that this message goes out to everyone, here, on this thread and to everyone struggling with depression or anxiety or low mood levels in general.
    I believe that there is a solution. And I believe wholeheartedly that there would not be a problem, without a potential solution somewhere out there. I’ve read 90 % of this message/comment thread … so to mostly everyone on here, I read your stuff 🙂
    This world is beautiful and you are all beautiful. Your eyes and your mind, your brain and spirit DECIDE what the world looks like. This is no joke. Your perspective is everything. Your beliefs are everything. Your brain paints the picture, your body experiences it. I have only experience and advice to offer, but life has shown me more than once that conquering depression or low dopamine levels or whatever the hell it is, that is negative or is interruptive, that it is a constant war. A never ending battle. But again, it all depends on your perspective. Fresh air, even when you don’t feel like it, get it. It’s good for you. Sunshine… great for the penial gland, can’t debate that. Water, swimming in ocean or gym or anywhere— amazing for you. Smiling, even faking it, great for you, tricks your mind and brain to believing you’re happy, or at least almost there. Laughter, works wonders. Watching comedies, playing table games with friends like Clue or Operation or cards or anything Twister or whatever in the world! As long as there is company, good, positive company then you’re on your way to better health mentally and physically, emotionally and spiritually. Reading valuable and inspiring material is always recommendable, depressed or not. Taking cold showers or at least rinsing off with cold water at the end- releases more dopamine. Shocks your system. Eating rich-dopamine foods like this article says, always a plus. Eating less in general, releases more dopamine. And I don’t mean starve yourself.. I mean, eat less 🙂 50- 100 calories a day less is a great start. Eating less carbs, or no carbs has amazing results! At least that did for me… I can also say from experience, prayer works. And you don’t even have to believe in God, or believe in anything! Just believing in prayer itself is enough, I think. Read articles & do more and more research
    … people all over the world agree meditation and prayer work miracles, whether you’re a believer or not. Something about talking it out and releasing all your anxiety upon someone else, someone bigger than you or bigger than the universe itself— something about trusting someone or something other than yourself, just brings that peace and serenity that is hard to find somewhere else, that calmness within that’s real and not a temporary, fake relief, but the prayer and meditation that lasts as long as you’re willing to do it, and believe that it works. Faith really does do it. And love? Love overcomes it all, truly. “The greatest of these is love” ..
    Love wins in the end, everybody knows that. 🙂
    By loving yourself, you learn how to love others and by loving others you learn to love the universe and everything else around you. Love conquers fear. There is no fear in love. Love yourself. And if you don’t, learn to. Read and read and watch documentaries, or videos of real life situations where people struggled with loving themselves but eventually found a way. Or should I say “love found a way.” Thing is, depression or low mood levels or depletion of dopamine, I think, interferes with love… loving yourself or other people. And that’s where it all starts. Vicious cycle that is. You hate yourself or don’t like yourself so you release that “I don’t like myself” into the world and the shame , and the blame, just projects into the atmosphere and the environment should I say, around you. You avoid people and situations where social events happen, you avoid your family and loved ones, and simply “don’t feel a thing” . You just exist. Well, who wants that life?! I sure don’t. And nor should anyone else! Just existing does not sound like what God intentended us to do, I’m sure, when He created us. And like I said, whether you’re a Christian or an atheist, if your life sucks, it sucks and I’ll argue that no one actually wants their life to suck, or their attitudes for that matter. So here’s my advice, if anyone wants it, it’s free 🙂 … 1) Find a good doctor, take blood tests, take all the kinds of tests you need to see what’s actually going on with you , 2) Find something or go back to something that you’re passionate about or think you’re passionate about, and DO IT !!!
    3) Maybe get some sort of a pet you can find comfort in. I’ve read a lot on people reporting they’re much happier just from either having a dog or a cat or any pet really.
    4) Avoid coffee. Tea is better, especially calming tea like chamomile, (also Oolong tea helps with aid loss) Just substituting fruit or flavored drinks with tea helps, that is not debatable.
    5) Vitamin D-eeeeeee , C & Iron = take it. Along with Omega 3s fish oil
    6) Take showers every day. Feeling low or depressed, take a shower, brush your teeth again , floss, put lotion on your legs or for guys maybe put cologne on or anything that shows “I am taking care of myself, because I love and respect myself” works, whether you think it does or doesn’t, your brain listens to you and this “taking care of yourself” affects you subconsciously for sure.
    7) Make a to do list every day morning or mid day. Check things off. This will give you sense of accomplishment, following of course more dopamine release. Yayyy
    8) Workout, exercise, move! Movement helps tremendously. Even a 30 minute walk is proven to help you feel better, duh.
    9) Find a spiritual thing you can do. Meditation, yoga, prayer, reading the Bible, listening to inspirational things, or motivational — anything that makes you believe in yourself and deters you from feeling like crap, do it. (of course only if it’s healthy and positive, and human friendly
    10) Essential oils. Diffuser at home, Lavender linen spray- anything that relaxes your spirit and mind surround yourself with it. Again, that is healthy and good for your well being and others of course.

    I have to go now.
    Hope I’ve helped somehow, if not, I’ll keep doing my research more and more and pray someday I’ll be able to truly help someone indeed.

  • I’m lucky to see this article and read the comments. Most of them are really interesting which I may try. God bless those behind this topic and appreciate their effort.

  • Shane you have so many questions about life, how to live life and it’s purpose. If you seriously want answers I suggest you read the New testament of the Bible, NIV is the best translation, believe me it will answer all your questions.?

  • Useless suggestions. Done all in the original article and they’ve done nothing to improve the original list of dopamine deficiency symptoms.

  • Hi everyone, I suffer from anxiety and slight depression. I have had the best results while eating 20 bananas a day (I know it sounds a bit crazy but it was 10 in a smoothie in the am and 10 bananas at lunch). This helped me quit coffee because I didn’t feel the need for it I had energy and mental alertness I was running to drink more water because of the sweet taste. I also used spotty bananas to avoid constipation. I had great bowel movements actually. For dinner I baked 5 medium potatoes and ate them with some lettuce leafs and green onion for flavor. I basically had my energy, digestion and happiness back . I was performing better than ever at work and my personal life improved as I had more energy and did not feel bloated so therefore more love making. I hope you guys give this a try I did it for 2 weeks and then I diminished to 6 bananas in the am and different vegan dishes throughout the day. But I always start my mornings with smoothies!

  • Magnesium , vitamin d3 , Ashwagandha , active b complex , zinc , iron , zero sugar , protein , healthy fats , zero caffeine , good sleep , exercise , vitamin c , healthy food .

  • I asked google how to reduce to much dopamine and this is what I found. I could find nothing on reducing dopamine. My daughter’s dopamine is off the charts and progesterone is almost non-existent. Poor girl.

  • Shane,
    You most probably are having dopamine deficiency. I had exactly same symptoms as you, except that I had oversleeping problem, and also had high desire for masturbation.
    Well, after fitting into society and acting in jobs that others could have endorsed me about my performance, responsibility and intelligence, I felt better.
    I also had something called inferiority complex, and that was due to my parents taking hard on me.
    My problem is partially fixed and I’m getting better and better everyday, and my overthinking is lowered also. I do drink Harmala teas, and plan to visit a very good psychiatrist which also does psychoanalysis/psychotherapy besides the medication.
    So stop detaching from the real world, and go outside. Try to enjoy nature. Go to a park and see children play. Go to the highest point of your city at night and enjoy the lights. Read pleasant story books. Listen to happy music. Try to analyze human behaviors and enjoy your ability to do so, look at them like funny livings, not as a highly intelligent kind which is here to show a perfect state of evolution. Return to childhood and see adults as children which are playing more complex games as they grow up.
    Don’t search for too much meaning in the life, we are just a complex neural network with hell plenty of electrical impulses. We are not superiors. So relax and live in the moment.

  • It is important to correct the statement that this is a deficiency in the brain. It is not possible to test dopamine or other neurotransmitters in the brain. Chemical imbalance theory is just that. In fact, some countries are insisting pharma take down these types of comments on their websites that, for eg..their antidepressant corrects chemical imbalance. Never and not able to be proven. However, if you deplete in the body then neurotransmitters do seem to impact mood. It can be a very confusing area to explore.
    Current theories though are suggesting inflammation. Seems that many treatments at some level are addressing inflammation.
    Make sure you take a broad approach with exercise, good diet and good quality fish oil or better yet oily fish. There is good research supporting omega 3, and exercise for depression and inflammation.

  • I wonder about people like me. I was born with the condition where my dopamine is low and serotonin is high. While I do drink coffee now, I didn’t for the first 42 years of my life. My magnesium is almost high. I have suffered with life long depression and a pharmacogenetic test found that I have a mutation that causes low dopamine. Will this list still be helpful for me.

  • “In many cases it, it is caused by actual physiologic changes in the brain” … Which cases are those? Last time I checked, there was little evidence supporting theories of causation like this.

  • I became addicted to snorting oxycodone a few years ago. My daughter died, my son who has down syndrome has a terminal illness. I was turned on to it by my brother and almost immediately became addicted. I was in a bad way that day and it was like a magic pill. I only did it once to twice a week for 4 years but it was affecting my brain chemicals afterwards. I would exercise and tan and have sex and try other ways to get out of the funk. After my car crash andmy son was hospitalized 6 times in a 6 month period, i made the stupid decision to take daily. I was going to pain management. It helped so much at first with depression, anxiety, energy and so much more! I am now of of that monster but take buprenorphine for pain and addiction. I also have anorexia but still about 20 lbs overweight. I have always been very shy and very self critical and always drank and did cocaine ct in social situations and avoid everyone but my family. I also lost 2 brothers, one who was my one and only friend besides my hubby and kids. I have been through so much and always considered my self having high willpower. I had oxy in my house for 4 years before I summoned to daily use. Iam sure my dopamine levels and serotin have been majorly lowered from the drug use! I am petrified of antidepressant because of fear of weigh gain! I have been taking ashwagandha, 5htp and st johns wort. I havnt noticed much but maybe slight improvement. I am going to try adding l tyrosine, maybe gaba but hear d it dosnt cross blood brain barrier, also also adding l tyrosine. I have a script for wellburtin but dont want to quit smoking! I was on it once but i was also taking oxy 2x a week so thats probably why i saw no benefits! Why is it that the only drug for dopamine is wellbutrin and side effect is smoking makes you sick! If this natural approach dosnt help I will try the wellbutrin but so scared to try ssri! I am a freak baou dieting and eat maybe 600 to 800 calories a day! I weigh 150 so I am still a chubetter! I am trying to slowly up ,my calories, and oh yeah I am a caffenine coffee freak! I mostly do that to speed my metabolism and between that and the nicotine I rarely want to eat. I think my body holds on to food when I do eat so maybe food will be beneficail to my mind as well as keeping me from getting fat. Anyone with any recommendations I will be so thankful. I also live in fear of my son, he is always sick and can go from bing oaky one day and sick the next. I purree his food, give him a ton of brething traetments daily and, insulin shots as well ,as all his needs he is very severe in every way and he also aspirates and is always on the verge and I am stressed as hell over all this in my life! Thanks for any advise

  • I am a 51 year old female that just found out I have Motor Neuron Disease Parkinson’s about a year and half, but I have been having signs of it for years, tremors, depression, body weakness. ECT. I honestly don’t think my doctor was reading the signs because of my gender and age. A few years ago I had my shoulder lock up on me and I was sent to a P.T since x-rays didn’t show any physical damage. My shaking was getting worse and I began falling. Only when my speech became so bad that it brought concern to my dentist was Parkinson’s even considered. He phoned my doctor with his concerns about my shaking and balance problems. By this time I was forgoing shots in the back of my neck for back and neck pain to which once again I was sent to a P.T (although x-rays showed no damage) I was told I had a few spurs which were most likely causing the pain. Here I was feeling like my whole body was falling apart and doctor could not find anything wrong, maybe in was all in my head? My doctor even seemed annoyed with me and things just kept progressing and I just kept it to myself, why bother going through testing and them finding nothing? Well, it was after my second P.T called my doctor about the weakness in my legs and arms, by this time I have developed a gait in my walk and I fell more frequently. Only then did my doctor send me to a specialist and it was found that I had Parkinson’s, and that I have had it for awhile. I think because I was a woman that my signs and symptoms weren’t taken seriously and therefor left untreated for so long,I was taking pramipexole dihydrochloride three times daily, I Was on carbidopa levodopa but only lasted 90 minutes then wore off.I found that none of the current medications worked effective for me.I got tired of using those medication so I decided to apply natural herbs formula that was prescribed to me by my second P.T, i purchase the herbal formula from totalcureherbsfoundation. com, There has been huge progression ever since I start the treatment plan which will last for 15 weeks usage.all the symptoms and sign has begin to disappear .

  • I am an RLS, anxiety sufferer with IBS and Celiac disease. I have been on clonazepam/Klonapin for many years, 6 mg at night. It is physically addictive and I need off. I have been aware for some years that my dopamine was low. If anyone has been on this drug and gotten off, please share. My efforts have failed. I have tried to got to Mirapex but was not successful, but feel the dr. didn’t want me off the clonazepam and pushed the change to one week. Pharmacist says that was a bad idea and what I’m asking is difficult but possible with withdrawl with each decrease of the clonazepam. Anyone who can share who has overcome the physical addiction to clonazepam would be greatly appreciated.

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