In addition to the fact that it contains caffeine, which is a natural energy supplement, coffee can also burn fat, lower stroke risk, and improve physical performance, according to medical experts.

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Who couldn’t use a little more energy? It’s very difficult to lead a healthy, fulfilling, and productive life if you’re too fatigued to work, take care of your family and home, or exercise. Luckily, there are a number of natural energy supplements that promise to lift fatigue and boost energy, but before you heed their siren call—and open your wallet—there are a few things that you need to know.

First, and most importantly, if low energy and fatigue is having a major effect on your daily life, you should consult your doctor. It could be a sign of a more serious condition, such as chronic fatigue syndrome, insomnia, vitamin deficiency, fibromyalgia, or depression. But if you’re healthy and looking for ways to kick up your energy levels, read about our top four natural energy supplements.

#1 Caffeine

At moderate doses, caffeine stimulates your central nervous system, making you feel more alert, awake and energized. No wonder more than 80 percent of Americans are coffee drinkers! For most healthy adults, up to 400 milligrams (mg) of caffeine per day—the amount in a Venti brewed coffee at Starbucks—doesn’t present a health risk. At higher doses, caffeine can produce symptoms of anxiety, nervousness and jitteriness. Most caffeine pills contain 100-200 mg each, and while caffeine content in energy drinks and “shots” varies, some approach or slightly exceed 400 mg.

#2 Coenzyme Q10 (CoQ10)

CoQ10 plays a vital role in energy metabolism in our cells. Your body makes CoQ10, and you get some from food. While CoQ10 supplements may benefit those who have certain hereditary disorders, there’s no evidence that it boosts energy in healthy individuals. Several studies have found that CoQ10 supplements don’t significantly improve exercise performance in healthy men.

#3 Creatine

Your body produces creatine, which helps supply energy to your cells. You also get small amounts if you eat meat or other animal foods. Creatine supplements can provide more energy to muscles, boosting sports performance, and it is being investigated as a treatment for several neurological diseases, but don’t consider it a go-to for boosting overall energy levels.

#4 B Vitamins

Vitamin B12 and the other B vitamins play essential roles in the complex biochemical machinery that releases energy from the food you eat. If you are B-deficient, it can indeed affect your energy levels, but if you take in more B vitamins from supplements or energy drinks than your body can use, you won’t become “super energized.” Your body will simply excrete the excess.

Natural Energy Supplements for Life

Food is fuel for our bodies, so what we eat affects how energetic we feel throughout the day. Build meals and snacks from a mix of high-quality carbohydrates for energy with some lean protein and healthy fat for staying power. Slow-digesting carbohydrates (“slow carbs”) like whole grains, whole fruits, vegetables or beans offer a steady supply of energy, while “fast carbs” like sugar and refined flour provide a temporary lift—followed by a crash. Eating every 3 to 5 hours also supports steady energy.

—Carrie Dennett, MPH, RDN