Appetite Suppressants May Cause Strokes

Manufacturers are pulling from shelves hundreds of prescription andover-the-counter drugs, including appetite suppressants like Acutrim and Dexatrimand certain formulations of cold remedies like Dimetapp, Contacand Triaminic, because they contain the ingredient phenylpropanolamine (PPA).

The Food and Drug Administration is drafting new rules to ban PPA because afive-year Yale University School of Medicine study found a small but significantincrease in the risk of bleeding stroke among women using products containingPPA.

In a second study, scientists reviewing 140 adverse events that involvedweight-loss supplements containing ephedra (ma huang) concluded that ephedraalkaloids pose a risk of high blood pressure, heart palpitations, slowed heartrate, stroke and seizures.

Both studies were released prior to publication to alert the public.

The New England Journal of Medicine,December 21, 2000.
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