Bergamot Benefits? This Citrus Fruit’s Oils Can Relieve Anxiety and Raise HDL (“Good”) Cholesterol

Bergamot benefits can help to relieve your anxiety and keep your cholesterol levels in check.

bergamot benefits

Bergamot oil is used to moisturize hair, tone skin, and as a natural deodorant.

© Slallison |

Bergamot is a small, pear-shaped citrus fruit that grows on small trees that are cultivated almost exclusively in coastal regions of southern Italy. It’s sometimes referred to as the bergamot orange, although its resemblance is closer to that of a lime. Bergamot essential oil, made mainly from the peels, is very aromatic and commonly used in aromatherapy and perfumery. Its scent is distinctly different from other citrus essential oils and has been found to contain compounds that effect the functioning of neurotransmitters in a way that decreases anxiety.[1-3] Research on aromatherapy indicates that various essential oils, including bergamot, can help to relieve stress, anxiety, depression and other mood disorders. Bergamot benefits include communicating signals to the olfactory system, stimulating the brain to exert neurotransmitters (e.g. serotonin and dopamine) to regulate mood.[1] Human studies have shown that aromatherapy treatment with bergamot essential oil reduces anxiety and other symptoms of physical and psychological stress.[2,3]

Bergamot Benefits: Essential Oil

One study published in Evidence-Based Complementary and Alternative Medicine looked at how bergamot benefits aromatherapy reduced anxiety in patients scheduled for day surgery.[2]

A total of 109 patients were randomly assigned to 30 minutes of bergamot essential oil aromatherapy using an ultrasonic aroma diffuser or placebo therapy (water vapor). All those exposed to bergamot essential oil aromatherapy showed a greater reduction in pre-operative anxiety than those in the control group. Compared to baseline, those undergoing the bergamot essential oil aromatherapy exhibited significant decreases in anxiety scores, heart rate, and blood pressure, whereas no changes were observed in those in the placebo group.

Bergamot Benefits: Standardized Fruit Extract


bergamot benefits

Bergamot fruit grows on small trees grown almost exclusively in coastal regions of southern Italy. Its oil is used to moisturize hair, tone skin, and as a natural deodorant. (Photo courtesy of HP Ingredients)

Bradenton, Fla.-based HP Ingredients, makers of the product Bergamonte®, made from BPF produced by H&AD SRL (Italy), offers this background on the citrus fruit:

“Bergamot (Citrus Bergamia Risso) is a citrus plant that grows almost exclusively in the narrow coastal Calabria region in Southern Italy, due to sensitivity to the weather and soil conditions. Bergamot juice was traditionally recognized by the local population as a remedy for supporting healthy cholesterol level and cardiovascular health. The medicinal use of bergamot, forgotten for decades, is now being rediscovered.

“The juice and albedo of bergamot has a unique profile of flavonoid and glycosides, such as neoeriocitrin, neohesperidin, naringin, rutin, neodesmin, rhoifolin, and poncirin. Naringin have been shown to be beneficial in animal models of atherosclerosis, while neoeriocitrin and rutin have been found to exhibit a strong capacity to prevent LDL from oxidation. Importantly, bergamot juice is rich in brutieridine and melitidine with an ability to inhibit HMG-CoA reductase.”

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Bergamot fruit, meanwhile, is practically inedible but is also packed with a remarkable spectrum of healing phytochemicals that are finally starting to be researched and documented.

The fruit is unique in both the types of phytochemicals it contains (mostly different types of flavonoids) as well as their large concentration. The fruit juice and its extract have been shown to improve many aspects of cardiovascular heath, including cholesterol and triglycerides, blood pressure, and blood vessel function.[4]

Some of bergomot’s flavonoid compounds are similar in structure and action to statin drugs and have been found to lower cholesterol.[4] Other bergamot compounds are powerful antioxidants that have an affinity for the blood vessels and have been shown to improve blood vessel health and function.[4]

Bergamonte® bergamot polypenolic extract is a standardized extract of bergamot fruit containing a minimum of 25 percent flavanones, including 1 percent Melitidine and 2 percent Bruteridine. These compounds have been proposed to lower cholesterol by working like statin drugs in that they inhibit the enzyme HMG-CoA reductase. Bergamonte® bergamot polypenolic extract is sold by a number of supplement companies in the United States and has been the subject of a number of animal and human clinical studies showing impressive results.

Bergamot Benefits for Cholesterol, Triglycerides, and Blood Sugar

Italian researchers studied bergamot polyphenolic fraction (BPF) in a randomized, double-blind, placebo-controlled trial involving 237 patients with high cholesterol.[4] Some of them also had features of the metabolic syndrome (high blood sugar, high triglycerides, and low HDL cholesterol). The subjects took either 500 mg or 1000 mg of bergamot polyphenolic fraction per day, or placebo, for 30 days.

The study’s results?

  • Those in the bergamot polyphenolic fraction groups experienced significant average reductions in total cholesterol and LDL cholesterol, and a significant increase in HDL cholesterol compared to those in the placebo group.
  • The 59 subjects with metabolic syndrome also experienced a significant decrease in their triglycerides. In that group, total cholesterol dropped from 278 to 199mg/ml, LDL dropped from 188 to 126mg/ml, and triglycerides dropped from 267 to 158 mg/ml.
  • Not only that, but HDL (“good” cholesterol) increased in all patients, up to a striking 64.6 percent. Wow!

Bergamot polyphenolic fraction also reduced blood sugar levels by an average of 15 to 25 percent and is therefore of potential benefit in those with prediabetes and metabolic syndrome. Overall, there was not much difference in the 500 mg dose compared to the 1000 mg dose for any of the measured parameters except HDL, which increased significantly more in the group taking the higher, 1000 mg per day dose.

Is Bergamot Becoming an Alternative to Statin Drugs?

The same group of researchers also conducted a study using a higher dose of bergamot extract as a substitute for statins in 32 patients who could not tolerate statins due to the side effects of these drugs.[4]

After stopping statins for two months, they took 500 mg of bergamot extract in capsule form three times a day for a total of 1500 mg per day. After 30 days, the average reduction in total cholesterol was 25 percent, with an average 27.6 percent reduction in LDL cholesterol. There was no reappearance of side effects.

How to Obtain Bergamot Benefits Yourself

For stress and anxiety: To get the anti-anxiety benefits of bergamot essential oil, you have many aromatherapy options. But first, you must make sure you purchase a 100 percent pure essential oil and not a synthetic “fragrance.” You then need a way to get the aroma chemicals into the air so you can breathe them in.

As in the aromatherapy study discussed above, you can use a specialized aromatherapy diffuser. Inhalation by diffusion is one of the most common applications of essential oils utilized in studies. Ultrasonic aroma diffusers, like the one used in the study described above, use water and ultrasonic technology to break aroma oils into microscopic particles that are suspended in the air. This method is ideal because it provides a long-lasting and easily-absorbed method of diffusion without damaging the aroma chemicals with heat.

Another simple option is to put a couple of drops of the essential oil in a large bowl of hot water and then lean over the bowl to inhale the steam.

For cholesterol and blood sugar: To get the benefits of bergamot extract for high cholesterol, triglycerides, or blood sugar, look for capsules or tablets at your local health food store that contain a standardized bergamot extract such as Bergamonte® Bergamot Polyphenolic Extract. Now Foods, for example, and Jarrow Formulas both manufacture supplements using this extract. Take 500 mg twice a day. Like all therapies for cardiovascular and metabolic health, you’ll get the best results with bergamot if you utilize it along with other natural and lifestyle therapies.

Since bergamot works like statin drugs by inhibiting the enzyme HMG-CoA reductase, it also—like statins—may deplete Coenzyme Q10 (CoQ10), an important compound essential for energy production. Therefore, be sure to supplement with 50 to 100 mg of hydrosoluble Ubiquinol CoQ10. For more ideas on how to treat you cholesterol and/or triglycerides naturally, see our comprehensive guide here. And don’t miss our blog on how black tea (not only green tea) can lower cholesterol naturally.

Share Your Experience

What about you? Have you experienced these amazing bergamot benefits? If so, did you use the citrus bergamot essential oils or the bergamot extracts in capsules or tablets? Tell us about your experience with bergamot benefits in the Comments section below. By doing so, you can encourage others who are seeking natural remedies to treat their health conditions.

[1] Curr Drug Targets. 2013 Jul;14(8):872-9.

[2] Evid Based Complement Alternat Med. 2013;2013:927419.

[3] Evid Based Complement Alternat Med. 2013;2013:853809.

[4] Fitoterapia. 2011 Apr;82(3):309–316.

Originally published in 2014, this post is regularly updated by the editors of University Health News.

As a service to our readers, University Health News offers a vast archive of free digital content. Please note the date published or last update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

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Kathleen Jade, ND

Dr. Kathleen Jade is a naturopathic physician and served for many years as the Medical Director and Editor-In-Chief of Natural Health Advisory Institute. She has been licensed as a primary … Read More

View all posts by Kathleen Jade, ND

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  • To me, this sounds worrisomely like something I would expect to hear from an allopathic doctor. “Oh, taking this drug is causing a nasty side effect? Okay, here’s a prescription for a second drug to counteract the undesirable consequences of taking the first drug.”

    It has already been scientifically established to my satisfaction that for most people simply artificially lowering LDL cholesterol levels by taking statins contributes virtually nothing to improving overall health or extending life. I would classify the effect of both statins and bergamot extract of reducing both cholesterol and Coenzyme Q10 production by inhibiting the action HMG-CoA reductase in the liver as being more properly classified as a seriously adverse side effect. That serves as reason enough for me to choose to leave both statins and bergamot extract entirely alone, thank you.

  • Ok Greg, but what is a person to do?? I have had familial cholesterol issues (espec. too low HDL) and need something that will work. It’s not a big deal to take extra CoQ10. A low dose of Simvastatin and Red Yeast Rice both helped but had side effects from the RYR so have decided to try Bergamonte. My doctor & I are still waiting for results but from all that I’ve heard & read, I’m very optimistic.

  • I began taking Bergamot, Serrapeptase and L-Arginine towards the end of January of 2017 and when I had my blood tested at the end of June it was simply amazing how much my cholesterol dropped. I wasn’t dangerous, to begin with but now I am around 177. The biggest improvement was my triglycerides which nearly dropped by half to 86. I don’t know which of these suppliments was the most profound but I am very happy with them. I take them first thing in the morning on an empty stomach and plan to continue. FYI…no side effects except I bruise much easier now. And yes, I do take 100 mg of Ubiquinol CoQ10 each day as well.

  • My Lp (a) levels are insanely high – 225+ I had quintuple bypass 10 years ago. I’m on Livalo (a statin that is supposedly easier on the liver) and Fenofibrate as Trigs stay around 150. I’ve read that Bergamot can drastically lower Lp (a) but only for a month or so then levels go back up. I want to try it anyway, but should I quit Livalo and Fenofibrate first? What would happen if I didn’t? Thank you!

  • I was on Bergamot (1,000 mg per day 2 caps 2x day) and Berberine (1500 mg per day 3 caps 3x day) for 7 weeks. My cholesterol dropped from 288 to 165. LDL dropped from 201 to 108. HDL also dropped (booo) from 78 to 49. I’m curious if the results were due to both supplements or just one. Im going to try a test of removing one supplement and retest in 8 weeks.

  • My cholesterol levels have been high for a long timeI had been on statins but did not like being unable to drink grapefruit juice nor did I like the side effects. They didn’t do that much either. I started taking 1500 mg of Bergamot three months ago and just had blood work a week ago. My triglycerides had dropped by 93 points and my LDL by 47 points. Everything is now in the upper normal range for the first time in years. I am dropping my intake to 1000 mg daily and see if that maintains the levels in that range or maybe a little lower..

  • Hello There. I found your weblog the use of msn. That is a really
    neatly written article. I will be sure to bookmark it and
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  • Is this safe to use with Brillinta? I’ve had 4 bypasses and cannot take statins. My body is fine but cholesterol very bad.

  • Triglycerides over 700…(familial) started using RYR/100 mg CoQ10/ Nutrim /Alpha lipoic acid/ fenugreek & papaya/ fresh lemon drink w/ olive oil. I can’t tolerate statins. Eating healthy….interested in Bergamot natural remedy

  • I am elderly live alone generally good health not on any medications( I am 93) but had developed a poor sleep pattern I infuse Bergamot at night time and now sleep very well Trouble is I remain sleepy half the next day I get my oils from a highly reputable source in the UK

    i use the bergamot oil in a diffuser and sleep very well Troubgbe is I am sleepy half the next day as well.

  • I took Jarrow’s Formula’s bergamot capsules 1000mg (500mg twice a day) for six months. When I did my blood test my LDL was not changed at all. So it did not work for me

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