Worried About Younger-Onset Alzheimer’s? Take Action Now

More and more, Alzheimer's disease is striking younger people. Fortunately, there are steps you can take to keep your mind sharp and lower your risk of younger-onset Alzheimer's.


We're seeing an increasing number of early-onset or younger-onset Alzheimer's disease. Certain lifestyle adjustments may help you ward off the condition.

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Do you think mild cognitive impairment (or “pre-dementia”) and Alzheimer’s affects only the old? Think again. Dementia symptoms now affect an increasing number of people in their 40s. The result: an increasing number of people being diagnosed with early-onset or younger-onset Alzheimer’s.

Mild cognitive impairment is a loss of memory and cognition. As it progresses, it can have you getting lost in your own neighborhood or forgetting the subject of the movie you just watched. Individuals with mild cognitive impairment have an increased risk of developing Alzheimer’s or dementia symptoms.

Research shows cognitive decline is beginning more frequently in adults around age 45[1]—a good 15 to 20 years earlier than in previous generations. About 10 percent of the 5.5 million Americans with Alzheimer’s are under the age of 65. Many of them began experiencing symptoms of mild cognitive impairment in their 30s, 40s, and 50s. Autopsies also show physical signs of Alzheimer’s are evident in the brains of people in their 40s who are still symptom-free.

Younger-Onset Alzheimer’s: Genetic Factors May Be Involved…

Early-onset Alzheimer’s is seen more often in individuals who have a parent or grandparent with the disease. A significant number of early-onset Alzheimer’s cases are linked to three different genes, making the genetic path of inheritance much stronger in early-onset Alzheimer’s.[2]

…But Lifestyle Trumps Even Genetic Predisposition

Because memory loss and cognitive decline can be traced to so many dietary and lifestyle factors, we can expect an increasing number of people to be affected earlier in life. Increasing numbers of children and young people now deal with obesity, lack of physical activity, inflammatory disorders, and diabetes, all factors that rob them of brain health.

Later in life, identifiable risk factors, such as hypertension,[3] accelerate cognitive decline in people under 65. For the middle-aged who are overweight, the risk of developing Alzheimer’s goes up 80 percent. Throw in a “pot belly,” or excess abdominal fat, and the risk triples and quadruples.[4]

With overall rates of mild cognitive impairment and Alzheimer’s climbing, we can expect to see the rates of early-onset mild cognitive impairment and Alzheimer’s climb as well. This makes adopting a brain-healthy diet and lifestyle as early as possible in life important. Not only should adults learn to support brain health, but parents should start their children on healthy diet and exercise plans to establish brain-healthy habits.

Steps You Can Take Now to Fend Off Younger-Onset Alzheimer’s

Many lifestyle factors that can start in youth have been identified with an increased risk of mild cognitive impairment and Alzheimer’s. They include:

  • Insulin resistance
  • Diabetes
  • Obesity and being overweight
  • Excess abdominal fat
  • Depression
  • High blood pressure
  • Elevated cholesterol
  • Lack of physical exercise
  • Lack of social stimulation

Adopting a more brain-health diet and lifestyle is not hard. The evidence supporting the preventive effects of regular exercise is substantial. Thirty minutes a day of cardiovascular exercise (even going for a walk) and strength training a few times a week can significantly lower risk. To reverse or reduce the risk of insulin resistance, one should switch to a lower-carb diet that is free of sweets, sodas and juice, and refined carbohydrates such as pasta, breads, pastries, rice, potatoes, and corn.

Eat plenty of leafy green produce, protein, and healthy fats, and be sure to include omega 3 fatty acids and vitamin D3. So don’t let the fact that your mom or Aunt Suzie had Alzheimer’s scare you into believing that you’re doomed to the same fate. Start now with these brain-healthy steps to enjoy sharp cognition as you enthusiastically move into your best years.

Share Your Experience

Now it’s your turn. Tell us in the Comments section below what you maybe be doing to prevent the onset of cognitive decline or Alzheimer’s in your life. Is it diet, or exercise, or specific supplements, or something else? Help our readers understand better what choices are available.

[1] Timing of onset of cognitive decline: results from Whitehall II prospective cohort study. BMJ 2012;344:d7622
[2] http://www.mayoclinic.com/health/alzheimers/AZ00009
[3] Hypertension and the rate of of cognitive decline in patients with dementia of the Alzheimer type. Alzheimer disease and associated disorders. Alzheimer Dis Assoc Disord.2004 Oct-Dec;18(4):208-13.
[4] Larger belly in mid-life increases risk of dementia. American Academy of Neurology. March 26, 2008.

Originally published in 2012, this post is regularly updated.

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UHN Staff

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  • To prevent cognitive decline as I age, I’m working toward a PhD in botanical medicine. In 2009 I finished my bachelor’s degree in Natural Health with highest honors. I then committed to both the master’s and PhD programs (because that gave me a substantial tuition discount). I finished the master’s program in Herbology, and continued on to the PhD program. I’m currently working on my theses – I have to write three short ones. I’ve completed the first one (Music Therapy: a drug-free approach to health and healing) and am working on the second (Non conventional health modalities). I exercise a few days a week, plus work on my little farm feeding goats and chickens, and working in my gardens. I hope these things prevent cognitive decline, but even if they don’t, I’m enjoying life. Oh, how old am I? How many trombones led the big parade (Music Man)?

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