Food & Mood: Hidden Trans-Fats Increase Risk of Depression Symptoms

Consumption of trans-fats is linked to a significantly increased risk for depression symptoms.

Trans-fats (or trans fatty acids) are artificial fats that are created in an industrial process.

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Isn’t it ironic that the very foods many of us crave (and often overeat) when we are depressed are the same foods that are causing, or at least contributing, to our depression symptoms in the first place? Such is the case for trans-fats, the industrially made fat found in packaged and fast foods. Not that we crave trans fats themselves, exactly; we just crave the convenient snack foods, baked goods, and fried fast foods that happen to be loaded with trans fats.

Research results

Consumption of trans-fats is linked to a significantly increased risk for depression symptoms. Spanish investigators, for instance, found that compared with people who consumed diets low in trans-fats, individuals with elevated levels of trans-fats had a 48% increased risk for depression.[1] The researchers followed over 12,000 Spanish university graduates, who initially had no depression symptoms, for over six years. They tracked their intakes of various types of fat and the occurrence of depression. Their aim was to assess the role of different types of dietary fat on risk for depression. The study researchers found a strong association between intake of trans-fats and depression that persisted even after controlling for many factors.

US trans fat consumption is excessive

While the results were not surprising to the researchers, they are important because no previous data had looked at trans-fat intake and the risk of depression symptoms. Furthermore, the researchers suggested that the findings should have major implications especially in the United States, where average trans-fat intake is extremely high compared to Spain where the study was conducted. Compared to Americans, whose trans-fat intake can make up 2.5% of total energy intake, the Spanish subjects had a low average trans-fat intake (0.4% of total energy). “So, the repercussion of these results might be really important in other settings such as the American population,” stated the investigators.

The reason trans-fats increase depression symptoms may be similar to why they increase risk for cardiovascular disease: inflammation and altered functioning of endothelial cells which line blood vessels. Both cardiovascular disease and depression are associated with increases in inflammation and dysfunction of endothelium, according the researchers, and trans-fats are known to cause both these problems.

What is trans-fat?

Trans-fats (or trans fatty acids) are artificial fats that are created in an industrial process that adds hydrogen to liquid vegetable oils to make them more solid. Another name for trans-fats is “partially hydrogenated oils.”  Trans-fats, according to the American Heart Association, are found especially in fried foods like French fries and doughnuts, and baked goods including pastries, pie crusts, biscuits, pizza dough, cookies, crackers, and stick margarines and shortenings. The World Health Organization and other organizations like the American Heart Organization recommend a limit of trans-fat intake of less than 1% of total energy.[2] According to the American Heart Association, that means if you need 2,000 calories a day, no more than 20 of those calories, which is less than 2 grams of trans-fats a day, should come from trans-fats. They note that given the amount of naturally occurring trans-fats you probably eat every day (mainly from cheese and other high fat dairy), this leaves virtually no room at all for industrially manufactured trans-fats.

So, as tempting as it is to reach for a bag of cookies to temporarily boost your mood, you may be worsening your mood and risking depression symptoms, not to mention cardiovascular disease, in the long run. Instead, why not try a comprehensive, natural approach to healing depression that targets the underlying cause. When you resolve the true underlying causes of your depression, you can say goodbye to it forever! But it is important to evaluate for yourself all of the major causes that might be contributing to your depression.


[1] Sánchez-Villegas A, Verberne L, De Irala J, et al. Dietary fat intake and the risk of depression: the SUN Project. PLoS One. 2011 Jan 26;6(1):e16268.

[2] http://www.heart.org/HEARTORG/GettingHealthy/FatsAndOils/Fats101/Trans-Fats_UCM_301120_Article.jsp

This post originally appeared in 2012 and has been updated.

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  • Setting goals, feeling grateful for the gift of life, and forgiveness can help you in dealing with depression. Writing down suppressed feelings in a journal, talking to friends or family about your problems can also help in the healing process. Meeting and talking to positive people and sharing their zest for life can make all the difference. Reading an inspirational book or watching a good movie can also help you in developing a positive attitude towards life.

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